Originally approved by the FDA to manage Type-2 diabetes, glucagon-like peptide-1 (GLP-1) receptor agonist drugs work to stimulate insulin secretion, lower blood sugar levels, and promote satiety. The overall therapeutic impact of these drugs, including meaningful weight loss, opened the door for the use of GLP-1s for other purposes.

Today, brands like Mounjaro, Ozempic, and Wegovy are marketed for weight loss. Their efficacy, along with social media promotion, has led to widespread use, with an estimated 2 to 3% of the U.S. population now taking a GLP-1 for diabetes, weight loss, or heart disease.

But rapid weight loss can trigger unwanted side effects, from muscle mass loss to slowed digestion. Adding protein and fiber to the diet can help to combat these common side effects. Food and supplement manufacturers offering such products could find a new audience in GLP-1 patients by using the right strategies to meet their evolving needs.

A Focus on Satiety

While not every GLP-1 patient experiences side effects, these drugs are known to reduce appetite, which can impact eating habits for many people. Consumers seeking balanced nutrition may turn to enhanced products that boost value.

When consuming smaller portion sizes, it’s important to find meal and snack options that offer nutrient density, focusing on satiety without bulk. Getting enough protein and fiber from whole foods like meat, animal products, and produce can be difficult, so products that add value through protein and fiber enhancement help to balance the scales and prevent issues like muscle loss and constipation.  

The Confluence of Protein and Digestive Health

In the health and wellness realm, it’s not unusual for products to focus on a specific ingredient type or health benefit. As a result, GLP-1 patients may struggle to find a single product that effectively pairs protein and fiber.

REBBL is among the best options for ready-to-drink (RTD) protein shakes, with over a dozen flavors featuring 20 to 32 grams of protein and up to five grams of dietary fiber. Oikos Pro offers a yogurt-based protein shake with 30 grams of protein and six grams of dietary fiber.

Protein and meal bars are another option where some crossover can be found. Wonderslim Protein & Fiber Bars feature 15 grams of protein and up to eight grams of dietary fiber, with five grams of sugar or less. 

In a similar vein, Ready Clean Protein Bars have 15 grams of fiber, seven grams of dietary fiber, along with gluten-free and non-GMO offerings. Consumers rave that they taste great.

The Complementary Nature of Collagen

Sagging skin is a common side effect of rapid weight loss. While it may not constitute a medical problem, it can impact self-esteem. Consuming collagen through enhanced foods or supplements could improve skin hydration and elasticity, potentially providing some relief for this potential side effect.

In studies on mice, collagen hydrolysate was found to improve glucose tolerance, enhance insulin secretion, and possibly improve the gut barrier to reduce GI discomfort, making it a welcome addition to GLP-1 diets. 

Supplements may be one way to add a daily intake of collagen, but some food and beverage manufacturers are hitting the mark, too. One notable example is Vital Proteins, offering Collagen Sparkling water with collagen peptides, zero added or artificial sugars, and a range of tasty flavors.

Related: Postbiotic-Enhanced Products: Beyond Probiotics for Gut Health

Supporting the GLP-1 Market

Protein and fiber are important inclusions in any diet, but striking the right balance is particularly critical for GLP-1 patients. Brands that offer multi-pronged solutions for known GLP-1 pain points have the potential to engage a growing niche market.

Key Takeaways

• Protein, fiber, and collagen help combat common side effects of rapid weight loss common to GLP-1 use, including loss of muscle mass, slowed digestion, and skin laxity
• Brands offering support for GLP-1 users could attract the 2 to 3% of the U.S. population estimated to take these drugs

To learn more about Symrise and more food trend insights, contact the team today!